The Mesothelioma and Radical Surgery Feasibility Study

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منابع مشابه

The MARS trial: mesothelioma and radical surgery.

The increasing incidence of malignant pleural mesothelioma has demanded the attention of thoracic surgeons worldwide. Can radical surgery cure mesothelioma or add usefully to the length and quality of life for its victims? The MARS (mesothelioma and radical surgery) trial is open and recruiting in Britain. If the trial proves feasible we will seek to make an international study.

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Extra-pleural pneumonectomy versus no extra-pleural pneumonectomy for patients with malignant pleural mesothelioma: clinical outcomes of the Mesothelioma and Radical Surgery (MARS) randomised feasibility study

BACKGROUND The effects of extra-pleural pneumonectomy (EPP) on survival and quality of life in patients with malignant pleural mesothelioma have, to our knowledge, not been assessed in a randomised trial. We aimed to assess the clinical outcomes of patients who were randomly assigned to EPP or no EPP in the context of trimodal therapy in the Mesothelioma and Radical Surgery (MARS) feasibility s...

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A feasibility study evaluating Surgery for Mesothelioma After Radiation Therapy: the "SMART" approach for resectable malignant pleural mesothelioma.

INTRODUCTION We developed an innovative approach for malignant pleural mesothelioma (MPM) with a short accelerated course of high-dose hemithoracic intensity-modulated radiation therapy (IMRT) followed by extrapleural pneumonectomy (EPP). This phase I/II study assessed the feasibility of Surgery for Mesothelioma After Radiation Therapy (SMART). METHODS All resectable clinical T1-3N0M0 histolo...

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Progress in Radical Surgery for Malignant Pleural Mesothelioma

Aim: Stages I and II malignant pleural mesothelioma (MPM) can be satisfactorily treated with extended extrapleural pneumonectomy (EPP). We modified our diagnostic methods and surgical techniques to improve outcome. Methods: 74 patients were treated with EPP, 33 from 1988 to May 2000 (first group), and 41 from June 2000 to 2010 (second group) and all underwent thoracoscopy without mediastinoscop...

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Mesothelioma and Radical Multimodality Therapy: Who

cer Institute Cancer Statistics Branch reports the incidence of invasive mesothelioma has steadily increased from 0.5 cases per 100,000 population in 1975 to 0.9 cases per 100,000 population in 1990.1a This translates to a modest increase from the 1,500 cases diagnosed in 1986.1b Additionally, there is a geographic maldistribution of cases in the United States, with an incidence in some areas o...

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ژورنال

عنوان ژورنال: Journal of Thoracic Oncology

سال: 2010

ISSN: 1556-0864

DOI: 10.1097/jto.0b013e3181ccba97